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A single amino acid change in histone H4 enhances UV survival and DNA repair in yeast

Single amino acid changes at specific DNA contacts of histones H3 and H4 generate SWI/SNF-independent (Sin) mutants in yeast. We have analyzed the effect of the Sin mutation at R45 of histone H4 on cell survival following UV irradiation, nucleotide excision repair (NER) and chromatin structure. We f...

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Détails bibliographiques
Auteurs principaux: Nag, Ronita, Gong, Feng, Fahy, Deirdre, Smerdon, Michael J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441814/
https://ncbi.nlm.nih.gov/pubmed/18508805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn311
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