Streptococcus pyogenes pSM19035 requires dynamic assembly of ATP-bound ParA and ParB on parS DNA during plasmid segregation

The accurate partitioning of Firmicute plasmid pSM19035 at cell division depends on ATP binding and hydrolysis by homodimeric ATPase δ(2) (ParA) and binding of ω(2) (ParB) to its cognate parS DNA. The 1.83 Å resolution crystal structure of δ(2) in a complex with non-hydrolyzable ATPγS reveals a uniq...

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Autores principales: Pratto, Florencia, Cicek, Aslan, Weihofen, Wilhelm A., Lurz, Rudi, Saenger, Wolfram, Alonso, Juan C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441792/
https://ncbi.nlm.nih.gov/pubmed/18477635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn170
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