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Streptococcus pyogenes pSM19035 requires dynamic assembly of ATP-bound ParA and ParB on parS DNA during plasmid segregation

The accurate partitioning of Firmicute plasmid pSM19035 at cell division depends on ATP binding and hydrolysis by homodimeric ATPase δ(2) (ParA) and binding of ω(2) (ParB) to its cognate parS DNA. The 1.83 Å resolution crystal structure of δ(2) in a complex with non-hydrolyzable ATPγS reveals a uniq...

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Detalhes bibliográficos
Main Authors: Pratto, Florencia, Cicek, Aslan, Weihofen, Wilhelm A., Lurz, Rudi, Saenger, Wolfram, Alonso, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441792/
https://ncbi.nlm.nih.gov/pubmed/18477635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn170
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