The Sac1 Phosphoinositide Phosphatase Regulates Golgi Membrane Morphology and Mitotic Spindle Organization in Mammals

Phosphoinositides (PIPs) are ubiquitous regulators of signal transduction events in eukaryotic cells. PIPs are degraded by various enzymes, including PIP phosphatases. The integral membrane Sac1 phosphatases represent a major class of such enzymes. The central role of lipid phosphatases in regulatin...

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Main Authors: Liu, Yang, Boukhelifa, Malika, Tribble, Emily, Morin-Kensicki, Elizabeth, Uetrecht, Andrea, Bear, James E., Bankaitis, Vytas A.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441670/
https://ncbi.nlm.nih.gov/pubmed/18480408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-12-1290
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