AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish Study of High Density Schizophrenia Families (ISHDSF)

BACKGROUND: The phosphatidylinositol 3-kinase (PI3K)-AKT signal transduction pathway is critical to cell growth and survival. In vitro functional studies indicate that the candidate schizophrenia susceptibility gene DTNBP1 influences AKT signaling to promote neuronal viability. The AKT1 gene has als...

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Autors principals: Thiselton, Dawn L, Vladimirov, Vladimir I, Kuo, Po-Hsiu, McClay, Joseph, Wormley, Brandon, Fanous, Ayman, O’Neill, Francis A, Walsh, Dermot, Van den Oord, Edwin JCG, Kendler, Kenneth S, Riley, Brien P
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441648/
https://ncbi.nlm.nih.gov/pubmed/17825267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.06.005
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