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Sequence-based prediction of protein-protein interactions by means of codon usage
We introduce a novel approach to predict interaction of two proteins solely by analyzing their coding sequences. We found that similarity in codon usage is a strong predictor of protein-protein interactions and, for high specificity values, is as sensitive as the most powerful current prediction met...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2441473/ https://ncbi.nlm.nih.gov/pubmed/18501006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-5-r87 |
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