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Pyrrolidine Dithiocarbamate Restores Endothelial Cell Membrane Integrity and Attenuates Monocrotaline-Induced Pulmonary Artery Hypertension
Monocrotaline (MCT)-induced pulmonary artery hypertension (PAH) in rats is preceded by an inflammatory response, progressive endothelial cell membrane disruption, reduction in the expression of caveolin-1 and reciprocal activation of STAT3 (PY-STAT3). Superoxide and NF-κB have been implicated in PAH...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2441448/ https://ncbi.nlm.nih.gov/pubmed/18390833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00069.2007 |
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