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Chromatin tethering effects of hNopp140 are involved in the spatial organization of nucleolus and the rRNA gene transcription
The short arms of five human acrocentric chromosomes contain ribosomal gene (rDNA) clusters where numerous mini-nucleoli arise at the exit of mitosis. These small nucleoli tend to coalesce into one or a few large nucleoli during interphase by unknown mechanisms. Here, we demonstrate that the N- and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440943/ https://ncbi.nlm.nih.gov/pubmed/18253863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11373-007-9226-7 |
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