Chromatin tethering effects of hNopp140 are involved in the spatial organization of nucleolus and the rRNA gene transcription

The short arms of five human acrocentric chromosomes contain ribosomal gene (rDNA) clusters where numerous mini-nucleoli arise at the exit of mitosis. These small nucleoli tend to coalesce into one or a few large nucleoli during interphase by unknown mechanisms. Here, we demonstrate that the N- and...

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Bibliografske podrobnosti
Main Authors: Tsai, Yi-Tzang, Lin, Chen-I, Chen, Hung-Kai, Lee, Kuo-Ming, Hsu, Chia-Yi, Yang, Shun-Jen, Yeh, Ning-Hsing
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2008
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440943/
https://ncbi.nlm.nih.gov/pubmed/18253863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11373-007-9226-7
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