PRO-INFLAMMATORY CYTOKINES FROM KUPFFER CELLS DOWNREGULATE HEPATOCYTE EXPRESSION OF ADRENOMEDULLIN BINDING PROTEIN-1

Polymicrobial sepsis is characterized by an early, hyperdynamic phase followed by a late hypodynamic phase. Adrenomedullin (AM), a vasodilatory peptide, inhibits this transition from the early phase to the late phase. Adrenomedullin binding protein-1 (AMBP-1) enhances AM-mediated activities. The dec...

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Autores principales: Jacob, Asha, Zhou, Mian, Wu, Rongqian, Halpern, Vivienne J., Ravikumar, Thanjavur S., Wang, Ping
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440713/
https://ncbi.nlm.nih.gov/pubmed/17490866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2007.03.010
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