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Determination of 8-Oxoguanine and 8-Hydroxy-2’-deoxyguanosine in the Rat Cerebral Cortex Using Microdialysis Sampling and Capillary Electrophoresis with Electrochemical Detection

A rapid and sensitive method to determine 8-oxoguanine (8oxoG) and 8-hydroxydeoxyguanosine (8OHdG), biomarkers for oxidative DNA damage, in cerebral cortex microdialysate samples using capillary electrophoresis with electrochemical detection was developed. Samples were concentrated on-column using p...

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Detalhes bibliográficos
Main Authors: Arnett, Stacy D., Osbourn, Damon M., Moore, Kimberly D., Vandaveer, Shannon S., Lunte, Craig E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440692/
https://ncbi.nlm.nih.gov/pubmed/15994136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2005.05.036
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