Rab35 and Its GAP EPI64C in T Cells Regulate Receptor Recycling and Immunological Synapse Formation

Upon antigen recognition, T-cell receptor (TCR/CD3) and other signaling molecules become enriched in a specialized contact site between the T cell and antigen-presenting cell, i.e. the immunological synapse (IS). Enrichment occurs via mechanisms that include polarized secretion from recycling endoso...

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Bibliografiska uppgifter
Huvudupphovsmän: Patino-Lopez, Genaro, Dong, Xiaoyun, Ben-Aissa, Khadija, Bernot, Kelsie M., Itoh, Takashi, Fukuda, Mitsunori, Kruhlak, Michael J., Samelson, Lawrence E., Shaw, Stephen
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2008
Ämnen:
Molecular Basis of Cell and Developmental Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440627/
https://ncbi.nlm.nih.gov/pubmed/18450757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800056200
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