Functional characterization of endogenous siRNA target genes in Caenorhabditis elegans

BACKGROUND: Small interfering RNA (siRNA) molecules mediate sequence specific silencing in RNA interference (RNAi), a gene regulatory phenomenon observed in almost all organisms. Large scale sequencing of small RNA libraries obtained from C. elegans has revealed that a broad spectrum of siRNAs is en...

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Bibliographic Details
Main Authors: Asikainen, Suvi, Heikkinen, Liisa, Wong, Garry, Storvik, Markus
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440555/
https://ncbi.nlm.nih.gov/pubmed/18522735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-270
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