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Central Role for MyD88 in the Responses of Microglia to Pathogen-Associated Molecular Patterns

Microglia, the innate immune effector cells of the CNS parenchyma, express TLR that recognize conserved motifs of microorganisms referred to as pathogen-associated molecular patterns (PAMP). All TLRs identified to date, with the exception of TLR3, use a common adaptor protein, MyD88, to transduce ac...

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Detalhes bibliográficos
Main Authors: Esen, Nilufer, Kielian, Tammy
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440502/
https://ncbi.nlm.nih.gov/pubmed/16709840
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