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Two-Crystal Structures of Tropomyosin C-Terminal Fragment 176–273: Exposure of the Hydrophobic Core to the Solvent Destabilizes the Tropomyosin Molecule
Tropomyosin (Tm) is a two-stranded α-helical coiled-coil protein, and when associated with troponin, it is responsible for the actin filament-based regulation of muscle contraction in vertebrate skeletal and cardiac muscles. It is widely believed that Tm adopts a flexible rod-like structure in which...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440446/ https://ncbi.nlm.nih.gov/pubmed/18339732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.126144 |
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