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Two-Crystal Structures of Tropomyosin C-Terminal Fragment 176–273: Exposure of the Hydrophobic Core to the Solvent Destabilizes the Tropomyosin Molecule

Tropomyosin (Tm) is a two-stranded α-helical coiled-coil protein, and when associated with troponin, it is responsible for the actin filament-based regulation of muscle contraction in vertebrate skeletal and cardiac muscles. It is widely believed that Tm adopts a flexible rod-like structure in which...

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書誌詳細
主要な著者: Minakata, Shiho, Maeda, Kayo, Oda, Naoko, Wakabayashi, Katsuzo, Nitanai, Yasushi, Maéda, Yuichiro
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440446/
https://ncbi.nlm.nih.gov/pubmed/18339732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.126144
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