Systemic Complement Activation in Age-Related Macular Degeneration

Dysregulation of the alternative pathway (AP) of complement cascade has been implicated in the pathogenesis of age-related macular degeneration (AMD), the leading cause of blindness in the elderly. To further test the hypothesis that defective control of complement activation underlies AMD, paramete...

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Bibliographic Details
Main Authors:	Scholl, Hendrik P. N., Issa, Peter Charbel, Walier, Maja, Janzer, Stefanie, Pollok-Kopp, Beatrix, Börncke, Florian, Fritsche, Lars G., Chong, Ngaihang V., Fimmers, Rolf, Wienker, Thomas, Holz, Frank G., Weber, Bernhard H. F., Oppermann, Martin
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2008
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2440421/ https://ncbi.nlm.nih.gov/pubmed/18596911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002593
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Systemic Complement Activation in Age-Related Macular Degeneration

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