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Genetic Basis of Virulence Attenuation Revealed by Comparative Genomic Analysis of Mycobacterium tuberculosis Strain H37Ra versus H37Rv

Tuberculosis, caused by Mycobacterium tuberculosis, remains a leading infectious disease despite the availability of chemotherapy and BCG vaccine. The commonly used avirulent M. tuberculosis strain H37Ra was derived from virulent strain H37 in 1935 but the basis of virulence attenuation has remained...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zheng, Huajun, Lu, Liangdong, Wang, Bofei, Pu, Shiying, Zhang, Xianglin, Zhu, Genfeng, Shi, Wanliang, Zhang, Lu, Wang, Honghai, Wang, Shengyue, Zhao, Guoping, Zhang, Ying
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2008
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440308/
https://ncbi.nlm.nih.gov/pubmed/18584054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002375
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