Blockade of adenosine A(2B) receptors ameliorates murine colitis

BACKGROUND AND PURPOSE: The adenosine 2B (A(2B)) receptor is the predominant adenosine receptor expressed in the colon. Acting through the A(2B) receptor, adenosine mediates chloride secretion, as well as fibronectin and interleukin (IL)-6 synthesis and secretion in intestinal epithelial cells. A(2B...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kolachala, V L, Ruble, B K, Vijay-Kumar, M, Wang, L, Mwangi, S, Figler, H E, Figler, R A, Srinivasan, S, Gewirtz, A T, Linden, J, Merlin, D, Sitaraman, S V
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440087/
https://ncbi.nlm.nih.gov/pubmed/18536750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.227
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