Na(+)/Ca(2+) exchanger inhibition exerts a positive inotropic effect in the rat heart, but fails to influence the contractility of the rabbit heart

Background and purpose: The Na(+)/Ca(2+) exchanger (NCX) may play a key role in myocardial contractility. The operation of the NCX is affected by the action potential (AP) configuration and the intracellular Na(+) concentration. This study examined the effect of selective NCX inhibition by 0.1, 0.3...

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Detalhes bibliográficos
Main Authors: Farkas, A S, Acsai, K, Nagy, N, Tóth, A, Fülöp, F, Seprényi, G, Birinyi, P, Nánási, P P, Forster, T, Csanády, M, Papp, J G, Varró, A, Farkas, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438973/
https://ncbi.nlm.nih.gov/pubmed/18332852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.83
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