Derivation of Aromatic Amino Acid Mutants from a Methanol-Utilizing Yeast, Hansenula polymorpha

Three classes of mutants, deregulated to enhance the flow of aromatic intermediates through the tryptophan biosynthetic branch, were obtained. 5-Fluorotryptophan, an antimetabolite of tryptophan, was employed to obtain one class of deregulated mutants. By sequential resistance development, three res...

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Bibliografske podrobnosti

izdano v:	Appl Environ Microbiol
Principais autores:	Denenu, Emmanuel O., Demain, Arnold L.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1981
Teme:	Metabolism, Growth, and Industrial Microbiology
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC243872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16345763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.41.5.1088-1096.1981
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