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Characterization of the pre-force-generation state in the actomyosin cross-bridge cycle

Myosin is an actin-based motor protein that generates force by cycling between actin-attached (strong binding: ADP or rigor) and actin-detached (weak binding: ATP or ADP·P(i)) states during its ATPase cycle. However, it remains unclear what specific conformational changes in the actin binding site t...

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Bibliografische gegevens
Hoofdauteurs: Sun, Mingxuan, Rose, Michael B., Ananthanarayanan, Shobana K., Jacobs, Donald J., Yengo, Christopher M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438420/
https://ncbi.nlm.nih.gov/pubmed/18552179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710793105
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