Combined effects of 5-Fluorouracil, Folinic acid and Oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: pharmacological basis to develop an active antitumor immunochemotherapy

BACKGROUND: Five-fluorouracil (FU), mainly associated with leucovorin (L), plays an essential role in chemotherapy of colorectal carcinoma. Moreover, FU ± L has been found to increase the expression of tumor-associated carcinoembryonic antigen (CEA), that may be an important target in therapeutic pr...

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Main Authors: Prete, Salvatore P, Turriziani, Mario, Massara, Maria C, De Rossi, Alessia, Correale, Pierpaolo, De Vecchis, Liana, Torino, Francesco, Bonmassar, Laura, Aquino, Angelo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438331/
https://ncbi.nlm.nih.gov/pubmed/18577244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-27-5
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