MicroRNA-Mediated Down-Regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg Cells: A Potential Pathogenetic Lesion in Hodgkin Lymphomas

PRDM1/Blimp-1, a master regulator in terminal B-cell differentiation, has been recently identified as a tumor suppressor target for mutational inactivation in diffuse large B-cell lymphomas of the activated B-cell type. Our studies here demonstrate that PRDM1/blimp-1 is also a target for microRNA (m...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Nie, Kui, Gomez, Mario, Landgraf, Pablo, Garcia, Jose-Francisco, Liu, Yifang, Tan, Leonard H.C., Chadburn, Amy, Tuschl, Thomas, Knowles, Daniel M., Tam, Wayne
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Investigative Pathology 2008
विषय:
Regular Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438301/
https://ncbi.nlm.nih.gov/pubmed/18583325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080009
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