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The antiarrhythmic effect of centrally administered rilmenidine involves muscarinic receptors, protein kinase C and mitochondrial signalling pathways

Background and purpose: We have previously demonstrated that stimulation of imidazoline receptors in the CNS prevented halothane–adrenaline arrhythmias during halothane anaesthesia and that stimulation of the vagus nerve may be critical to this effect. However, details of the mechanism(s) involved a...

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Detalhes bibliográficos
Main Authors: Iwasaki, M, Hayashi, Y, Kamibayashi, T, Yamatodani, A, Mashimo, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438259/
https://ncbi.nlm.nih.gov/pubmed/18297108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.35
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