High-Fidelity DNA Polymerase Enhances the Sensitivity of a Peptide Nucleic Acid Clamp PCR Assay for K-ras Mutations

Sensitive detection of tumor-specific point mutations is of interest in both the early detection of cancer and the monitoring of treatment at a molecular level. Recently, peptide nucleic acid (PNA) clamp real-time PCR has provided a time-sparing and sensitive method for the detection of mutations in...

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Hlavní autoři: Gilje, Bjørnar, Heikkilä, Reino, Oltedal, Satu, Tjensvoll, Kjersti, Nordgård, Oddmund
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2008
Témata:
Technical Advances
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438201/
https://ncbi.nlm.nih.gov/pubmed/18556764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2008.070183
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