5-Aza-2′-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene

BACKGROUND AND PURPOSE: The connexin (Cx) 32 gene, a member of the gap junction gene family, acts as a tumour suppressor gene in human renal cell carcinoma (RCC) and is down-regulated by the hypermethylation of CpG islands in a promoter region of the Cx gene. The current study investigated whether t...

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Autores principales: Hagiwara, H, Sato, H, Ohde, Y, Takano, Y, Seki, T, Ariga, T, Hokaiwado, N, Asamoto, M, Shirai, T, Nagashima, Y, Yano, T
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2437922/
https://ncbi.nlm.nih.gov/pubmed/18264126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.17
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