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5-Aza-2′-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene
BACKGROUND AND PURPOSE: The connexin (Cx) 32 gene, a member of the gap junction gene family, acts as a tumour suppressor gene in human renal cell carcinoma (RCC) and is down-regulated by the hypermethylation of CpG islands in a promoter region of the Cx gene. The current study investigated whether t...
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Κύριοι συγγραφείς: | , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
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Nature Publishing Group
2008
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2437922/ https://ncbi.nlm.nih.gov/pubmed/18264126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.17 |
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