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CXCL10-Producing Mucosal CD4(+) T Cells, NK Cells, and NKT Cells Are Associated with Chronic Colitis in IL-10(−/−) Mice, Which Can Be Abrogated by Anti-CXCL10 Antibody Inhibition
We have shown previously that there is a temporal increase in the levels of CXCL10 and CXCR3 mRNA during spontaneous murine colitis. We now show that CXCL10 is significantly expressed by mucosal CD4(+) T cells, natural killer (NK) cells, and NKT cells, but not by dendritic cells (DCs), during chroni...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435497/ https://ncbi.nlm.nih.gov/pubmed/18370870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2007.0059 |
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