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Differential Genotype Dependent Inhibition of CYP2C9 in Humans
The effect of genetic polymorphisms in drug metabolizing enzymes (e.g., CYP2C9*3) on drug clearance have been well characterized but much less is known about whether these polymorphisms alter susceptibility to drug-drug interactions. Previous in-vitro work has demonstrated genotype-dependent inhibit...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435413/ https://ncbi.nlm.nih.gov/pubmed/18378563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.020396 |
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