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ONCOLOGIC PHASE 0 TRIALS INCORPORATING CLINICAL PHARMACODYNAMICS: FROM CONCEPT TO THE PATIENT

The United States Food and Drug Administration recently issued an Exploratory Investigational New Drug Guidance that provides a platform for the evaluation of targeted anticancer agents in small, early phase human clinical trials that can be used to establish the feasibility of proof-of-principle ta...

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Detalhes bibliográficos
Main Authors: Doroshow, James H., Parchment, Ralph E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435409/
https://ncbi.nlm.nih.gov/pubmed/18559579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4562
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