Essential CDK1 inhibitory role for separase during meiosis I in vertebrate oocytes

Separase not only triggers anaphase of meiosis I by proteolytic cleavage of cohesin on chromosome arms; in vitro vertebrate separase also acts as a direct inhibitor of cyclin-dependent kinase 1 (Cdk1) upon liberation from inhibitory securin. Blocking separase-Cdk1 complex formation by microinjection...

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Detaylı Bibliyografya
Asıl Yazarlar: Gorr, Ingo H., Reis, Alexandra, Boos, Dominik, Wühr, Martin, Madgwick, Suzanne, Jones, Keith T., Stemmann, Olaf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435240/
https://ncbi.nlm.nih.gov/pubmed/16906143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1467
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