Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-γ Agonists

Microglia and astrocytes express numerous members of the Toll-like receptor (TLR) family that are pivotal for recognizing conserved microbial motifs expressed by a wide array of pathogens. Despite the critical role for TLRs in pathogen recognition, when dysregulated these pathways can also exacerbat...

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Bibliographic Details
Main Authors: Gurley, Catherine, Nichols, Jessica, Liu, Shuliang, Phulwani, Nirmal K., Esen, Nilufer, Kielian, Tammy
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435222/
https://ncbi.nlm.nih.gov/pubmed/18584038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/453120
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