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BMP Signaling Is Required for RUNX2-Dependent Induction of the Osteoblast Phenotype
RUNX2 expression in mesenchymal cells induces osteoblast differentiation and bone formation. BMP blocking agents were used to show that RUNX2-dependent osteoblast differentiation and transactivation activity both require BMP signaling and, further, that RUNX2 enhances the responsiveness of cells to...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435171/ https://ncbi.nlm.nih.gov/pubmed/16598384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.060109 |
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