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VE-statin/egfl7 regulates vascular elastogenesis by interacting with lysyl oxidases

We previously characterized VE-statin/egfl7, a protein that is exclusively secreted by endothelial cells and modulates smooth muscle cell migration. Here, we show that VE-statin/egfl7 is the first known natural negative regulator of vascular elastogenesis. Transgenic mice, expressing VE-statin/egfl7...

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Detalhes bibliográficos
Main Authors: Lelièvre, Etienne, Hinek, Aleksander, Lupu, Florea, Buquet, Christelle, Soncin, Fabrice, Mattot, Virginie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435125/
https://ncbi.nlm.nih.gov/pubmed/18497746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.103
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