Differential contribution of TAP and tapasin to HLA class I antigen expression

Expression of class I human leucocyte antigens (HLA) on the surface of malignant cells is critical for their recognition and destruction by cytotoxic T lymphocytes. Surface expression requires assembly and folding of HLA class I molecules in the endoplasmic reticulum with the assistance of proteins...

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Bibliographic Details
Main Authors: Belicha-Villanueva, Alan, McEvoy, Sarah, Cycon, Kelly, Ferrone, Soldano, Gollnick, Sandra O, Bangia, Naveen
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2008
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2434385/
https://ncbi.nlm.nih.gov/pubmed/18194274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02746.x
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