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Host factor I, Hfq, binds to Escherichia coli ompA mRNA in a growth rate-dependent fashion and regulates its stability

The stability of the ompA mRNA depends on the bacterial growth rate. The 5′ untranslated region is the stability determinant of this transcript and the target of the endoribonuclease, RNase E, the key player of mRNA degradation. An RNA-binding protein with affinity for the 5′ untranslated region omp...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Vytvytska, Oresta, Jakobsen, Jimmy S., Balcunaite, Gina, Andersen, Jens S., Baccarini, Manuela, von Gabain, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24336/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14118
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