A Leishmania infantum cytosolic tryparedoxin activates B cells to secrete interleukin-10 and specific immunoglobulin

The immune evasion mechanisms of pathogenic trypanosomatids involve a multitude of phenomena such as the polyclonal activation of lymphocytes, cytokine modulation and the enhanced detoxification of oxygen reactive species. A trypanothione cascade seems to be involved in the detoxification process. I...

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Autores principales: Menezes Cabral, Sofia, Leal Silvestre, Ricardo, Moreira Santarém, Nuno, Costa Tavares, Joana, Franco Silva, Ana, Cordeiro-da-Silva, Anabela
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2008
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2433312/
https://ncbi.nlm.nih.gov/pubmed/18028371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02725.x
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