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Characterization of suppressive oligodeoxynucleotides that inhibit Toll-like receptor-9-mediated activation of innate immunity

Synthetic oligodeoxynucleotides containing unmethylated CpG sequences (CpG-ODNs) stimulate Toll-like receptor-9 (TLR-9), thereby activating innate immunity. Stimulatory CpG-ODNs have been shown to be valuable in modifying immune responses in allergy, infection and cancer. Recently, it has been repor...

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Autores principales: Peter, Mirjam, Bode, Konrad, Lipford, Grayson B, Eberle, Florian, Heeg, Klaus, Dalpke, Alexander H
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2433270/
https://ncbi.nlm.nih.gov/pubmed/17961163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02718.x
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