Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor binding sites

BACKGROUND: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (TFBSs) occur within an interval [-300, 0] bases upstream of a transcription start site (TSS). Although some programs for i...

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Huvudupphovsmän: Kim, Nak-Kyeong, Tharakaraman, Kannan, Mariño-Ramírez, Leonardo, Spouge, John L
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2008
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432075/
https://ncbi.nlm.nih.gov/pubmed/18533028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-262
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