Genetic diversity of vaccine candidate antigens in Plasmodium falciparum isolates from the Amazon basin of Peru

BACKGROUND: Several of the intended Plasmodium falciparum vaccine candidate antigens are highly polymorphic and could render a vaccine ineffective if their antigenic sites were not represented in the vaccine. In this study, characterization of genetic variability was performed in major B and T-cell...

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Hlavní autoři: Chenet, Stella M, Branch, OraLee H, Escalante, Ananias A, Lucas, Carmen M, Bacon, David J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432069/
https://ncbi.nlm.nih.gov/pubmed/18505558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-93
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