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The M235T Polymorphism in the AGT Gene and CHD Risk: Evidence of a Hardy-Weinberg Equilibrium Violation and Publication Bias in a Meta-Analysis

BACKGROUND: The M235T polymorphism in the AGT gene has been related to an increased risk of hypertension. This finding may also suggest an increased risk of coronary heart disease (CHD). METHODOLOGY/PRINCIPAL FINDINGS: A case-cohort study was conducted in 1,732 unrelated middle-age women (210 CHD ca...

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Detalhes bibliográficos
Main Authors: Zafarmand, Mohammad Hadi, van der Schouw, Yvonne T., Grobbee, Diederick E., de Leeuw, Peter W., Bots, Michiel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432037/
https://ncbi.nlm.nih.gov/pubmed/18575631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002533
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