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TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4(+)CD8(+) double-positive stage
The TLX1/HOX11 homeobox gene is frequently activated in T-cell acute lymphoblastic leukemia (T-ALL) by the t(10;14)(q24;q11) and t(7;10)(q35;q24) chromosomal translocations or by as yet unknown transcriptional mechanisms in the absence of 10q24 cytogenetic abnormalities. Almost all TLX1(+) T-ALLs ex...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2431114/ https://ncbi.nlm.nih.gov/pubmed/16398656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2005.05850.x |
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