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Transmembrane Segment 6 of the Glut1 Glucose Transporter Is an Outer Helix and Contains Amino Acid Side Chains Essential for Transport Activity

Experimental data and homology modeling suggest a structure for the exofacial configuration of the Glut1 glucose transporter in which 8 transmembrane helices form an aqueous cavity in the bilayer that is stabilized by four outer helices. The role of transmembrane segment 6, predicted to be an outer...

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Bibliografski detalji
Glavni autori: Mueckler, Mike, Makepeace, Carol
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431073/
https://ncbi.nlm.nih.gov/pubmed/18245775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708896200
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