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Role of S3 and S4 Transmembrane Domain Charged Amino Acids in Channel Biogenesis and Gating of KCa2.3 and KCa3.1

The role of positively charged arginines in the fourth transmembrane domain (S4) and a single negatively charged amino acid in the third transmembrane domain (S3) on channel biogenesis and gating of voltage-gated K(+) channels (Kv) has been well established. Both intermediate (KCa3.1) and small (KCa...

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Autores principales: Gao, Yajuan, Chotoo, Cavita K., Balut, Corina M., Sun, Fei, Bailey, Mark A., Devor, Daniel C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431042/
https://ncbi.nlm.nih.gov/pubmed/18227067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708022200
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