Novel Role of Antioxidant-1 (Atox1) as a Copper-dependent Transcription Factor Involved in Cell Proliferation

Copper plays a fundamental role in regulating cell growth. Many types of human cancer tissues have higher copper levels than normal tissues. Copper can also induce gene expression. However, transcription factors that mediate copper-induced cell proliferation have not been identified in mammals. Here...

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Bibliographic Details
Main Authors: Itoh, Shinichi, Kim, Ha Won, Nakagawa, Osamu, Ozumi, Kiyoshi, Lessner, Susan M., Aoki, Hiroki, Akram, Kamran, McKinney, Ronald D., Ushio-Fukai, Masuko, Fukai, Tohru
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Transcription, Chromatin, and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431038/
https://ncbi.nlm.nih.gov/pubmed/18245776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709463200
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