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Isolated Cytochrome c Oxidase Deficiency in G93A SOD1 Mice Overexpressing CCS Protein

G93A SOD1 transgenic mice overexpressing CCS protein develop an accelerated disease course that is associated with enhanced mitochondrial pathology and increased mitochondrial localization of mutant SOD1. Because these results suggest an effect of mutant SOD1 on mitochondrial function, we assessed t...

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Détails bibliographiques
Auteurs principaux: Son, Marjatta, Leary, Scot C., Romain, Nadine, Pierrel, Fabien, Winge, Dennis R., Haller, Ronald G., Elliott, Jeffrey L.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431012/
https://ncbi.nlm.nih.gov/pubmed/18334481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708523200
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