Killing K Channels with TEA(+)

Tetraethylammonium (TEA(+)) is widely used for reversible blockade of K channels in many preparations. We noticed that intracellular perfusion of voltage-clamped squid giant axons with a solution containing K(+) and TEA(+) irreversibly decreased the potassium current when there was no K(+) outside....

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Bibliographic Details
Main Authors: Khodakhah, Kamran, Melishchuk, Alexey, Armstrong, Clay M.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC24309/
https://ncbi.nlm.nih.gov/pubmed/9371846
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