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Enzymatically inactive U(S)3 protein kinase of Marek’s disease virus (MDV) is capable of depolymerizing F-actin but results in accumulation of virions in perinuclear invaginations and reduced virus growth

Marek’s disease (MD) is a highly contagious, lymphoproliferative disease of chickens caused by the cell-associated MD virus (MDV), a member of the alphaherpesvirus subfamily. In a previous study we showed that the absence of the serine-threonine protein kinase (pU(S)3) encoded in the MDV unique-shor...

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Main Authors: Schumacher, Daniel, McKinney, Caleb, Kaufer, Benedikt B., Osterrieder, Nikolaus
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430872/
https://ncbi.nlm.nih.gov/pubmed/18304599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.01.026
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