Plasmodium vivax trophozoites insensitive to chloroquine

BACKGROUND: Plasmodium vivax is a major cause of malaria and is still primarily treated with chloroquine. Chloroquine inhibits the polymerization of haem to inert haemozoin. Free haem monomers are thought to catalyze oxidative damage to the Plasmodium spp. trophozoite, the stage when haemoglobin cat...

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Bibliografiske detaljer
Main Authors:	Sharrock, Wesley W, Suwanarusk, Rossarin, Lek-Uthai, Usa, Edstein, Michael D, Kosaisavee, Varakorn, Travers, Thomas, Jaidee, Anchalee, Sriprawat, Kanlaya, Price, Ric N, Nosten, François, Russell, Bruce
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2008
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2430579/ https://ncbi.nlm.nih.gov/pubmed/18505560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-94
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Plasmodium vivax trophozoites insensitive to chloroquine

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