Plasmodium vivax trophozoites insensitive to chloroquine

BACKGROUND: Plasmodium vivax is a major cause of malaria and is still primarily treated with chloroquine. Chloroquine inhibits the polymerization of haem to inert haemozoin. Free haem monomers are thought to catalyze oxidative damage to the Plasmodium spp. trophozoite, the stage when haemoglobin cat...

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Detalhes bibliográficos
Main Authors: Sharrock, Wesley W, Suwanarusk, Rossarin, Lek-Uthai, Usa, Edstein, Michael D, Kosaisavee, Varakorn, Travers, Thomas, Jaidee, Anchalee, Sriprawat, Kanlaya, Price, Ric N, Nosten, François, Russell, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430579/
https://ncbi.nlm.nih.gov/pubmed/18505560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-94
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