Stargazin attenuates intracellular polyamine block of calcium-permeable AMPARs

Endogenous polyamines profoundly affect the activity of various ion channels, including that of calcium-permeable AMPA-type glutamate receptors (CP-AMPARs). Here we show that stargazin, a transmembrane AMPAR regulatory protein (TARP) known to influence transport, gating and desensitization of AMPARs...

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Autori principali: Soto, David, Coombs, Ian D., Kelly, Leah, Farrant, Mark, Cull-Candy, Stuart G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430330/
https://ncbi.nlm.nih.gov/pubmed/17873873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1966
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