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Src-family kinases in the development and therapy of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia

The BCR-ABL kinase inhibitor imatinib has shown significant efficacy in chronic myeloid leukemia (CML) and is the standard front-line therapy for patients in chronic phase. However, a substantial number of patients are either primarily refractory or acquire resistance to imatinib. While a number of...

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Detalhes bibliográficos
Autor principal: Li, Shaoguang
Formato: Artigo
Idioma:Inglês
Publicado em: Informa Healthcare 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430171/
https://ncbi.nlm.nih.gov/pubmed/18203007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428190701713689
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