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Circulating Precursor Levels of Endothelin-1 and Adrenomedullin, Two Endothelium-Derived, Counteracting Substances, in Sepsis

Plasma levels of endothelin-1 (ET-1) and adrenomedullin (ADM), two opposingly acting peptides, correlate with mortality in endotoxemia, but their measurement is cumbersome. New sandwich assays have been introduced that measure more stable precursor fragments. The objective of this study was to inves...

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Autori principali: Schuetz, Philipp, Christ-Crain, Mirjam, Morgenthaler, Nils G., Struck, Joachim, Bergmann, Andreas, Müller, Beat
Natura: Artigo
Lingua:Inglês
Pubblicazione: Informa Healthcare 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430170/
https://ncbi.nlm.nih.gov/pubmed/18080871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10623320701678326
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